Category: Uncategorized
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Carbonic Anhydrase and Wnt/β-Catenin Dual inhibitors with Potent Activity against MDR cells
We synthesized new pyrrole and indole derivatives as human carbonic anhydrase (hCA) inhibitors with the potential to inhibit the Wnt/β-catenin signaling pathway. The presence of both N1-(4-sulfonamidophenyl) and 3-(3,4,5-trimethoxyphenyl)substituents was essential for strong…
DDSC
Department of Drug Chemistry and Technologies
Sapienza University of Rome
Laboratory affiliated to Istituto Pasteur Italia
Fondazione Cenci Bolognetti
Piazzale Aldo Moro 5, I-00185 Roma, Italy
Phone: +39 06 4991 3800 – Fax: +39 06 49913993
Email: info@romanosilvestri.it
